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Mouse Anti-Avermectin (AVM) Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for avermectin. It is purified by protein A. It can be applied to ELISA, WB, FIA and CLIA assays of avermectin. The antigen for this antibody is VG8F247.
Specifications
Target Information
Avermectin is a macrocyclic lactone antibiotic that targets the nervous systems of parasites. It binds to glutamate-gated chloride channels in the neurons and muscle cells of nematodes and arthropods, increasing the permeability of these channels to chloride ions. This leads to hyperpolarization of the nerve and muscle cells, causing paralysis and death of the parasites. Avermectin is effective against a wide range of endoparasites and ectoparasites in livestock and pets. Its specific action on parasite nervous systems makes it a valuable target for antibody development to enhance detection and monitoring in veterinary medicine, supporting effective parasite control and animal health.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Wang, Chunmei, et al. "A monoclonal antibody-based ELISA for multiresidue determination of avermectins in milk." Molecules 17.6 (2012): 7401-7414. https://doi.org/10.3390/molecules17067401
