Recombinant Mouse Glycogen Phosphorylase, Muscle Form (Pygm), N-His

In mice, Glycogen Phosphorylase, Muscle Form (Pygm) is a key enzyme that plays a crucial role in glycogenolysis, the breakdown of glycogen into glucose-1-phosphate. This process is essential for providing energy for muscle contraction and other cellular activities. Pygm is primarily expressed in skeletal muscles, but it is also found in other tissues such as the brain, lymphoid tissues, and blood. Pygm is involved in various physiological processes, including insulin and glucagon signaling pathways, insulin resistance, and necroptosis. It is also implicated in immune responses and has been associated with pathological states like McArdle disease, schizophrenia, and cancer. Pygm is regulated by reversible phosphorylation and allosteric changes, and its activity is crucial for maintaining energy balance in cells. Overall, Pygm is a multifunctional protein with diverse applications in research, particularly in understanding glycogen metabolism, muscle function, and related diseases.