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Recombinant Guinea Pig Insulin (INS), N-GST

Cat. No.AP4C386

Product TypeAnimal Proteins

Size

Product Overview

BioVenic's Recombinant Guinea Pig Insulin (INS), N-GST is a recombinant protein expressed from E.coli. Its predicted molecular weight is 42.2 kDa. The purity is> 90%.

Specifications

Type Recombinant Protein
Species Guinea pig
Expression System E.coli
Purity > 90%
Endotoxin < 1.0 EU/μg
Predicted Molecular Weight 42.2 kDa
Physical State Lyophilized
Formulation 20 mM Tris, 150 mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.

Target Information

Guinea pig Insulin (INS) is a peptide hormone produced by the beta cells of the pancreas, playing a vital role in regulating carbohydrate, lipid, and protein metabolism. It promotes glucose uptake by cells, particularly in the liver, adipose tissue, and skeletal muscle, and inhibits gluconeogenesis in the liver. In guinea pigs, insulin has a potency of 8.5 to 9.0 i.u. per mg when measured by its ability to lower blood glucose levels. This hormone is essential for maintaining energy balance and supporting growth and development. Insulin deficiency in guinea pigs can lead to diabetes mellitus, with symptoms such as hyperglycemia and glucosuria. Successful treatment of insulin-dependent diabetes in guinea pigs using long-acting insulin glargine has been reported, highlighting the importance of insulin in managing diabetes in these animals. Additionally, insulin is used in research for developing diagnostic tools, such as anti-insulin antibodies for detecting insulin in guinea pigs.

Protein Guinea Pig Insulin (INS)
Protein Synonym INS
Gene ID 100379579
EC No. P01329

Shipping and Storage

This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 20 mM Tris, 150 mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.
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