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Recombinant Guinea Pig Insulin (INS), N-GST
Product Overview
BioVenic's Recombinant Guinea Pig Insulin (INS), N-GST is a recombinant protein expressed from E.coli. Its predicted molecular weight is 42.2 kDa. The purity is> 90%.
Specifications
Target Information
Guinea pig Insulin (INS) is a peptide hormone produced by the beta cells of the pancreas, playing a vital role in regulating carbohydrate, lipid, and protein metabolism. It promotes glucose uptake by cells, particularly in the liver, adipose tissue, and skeletal muscle, and inhibits gluconeogenesis in the liver. In guinea pigs, insulin has a potency of 8.5 to 9.0 i.u. per mg when measured by its ability to lower blood glucose levels. This hormone is essential for maintaining energy balance and supporting growth and development. Insulin deficiency in guinea pigs can lead to diabetes mellitus, with symptoms such as hyperglycemia and glucosuria. Successful treatment of insulin-dependent diabetes in guinea pigs using long-acting insulin glargine has been reported, highlighting the importance of insulin in managing diabetes in these animals. Additionally, insulin is used in research for developing diagnostic tools, such as anti-insulin antibodies for detecting insulin in guinea pigs.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 20 mM Tris, 150 mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.