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Recombinant Chicken Metalloproteinase Inhibitor 3 (TIMP3), N-His
Product Overview
BioVenic's Recombinant Chicken Metalloproteinase Inhibitor 3 (TIMP3), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 24.5 kDa. The purity is>90% (SDS-PAGE).
Specifications
Target Information
Chicken metalloproteinase inhibitor 3 (TIMP3) serves as a regulatory protein that controls the activity of matrix metalloproteinases (MMPs), enzymes that are crucial for the degradation of the extracellular matrix. In chickens, TIMP3 is essential for preserving tissue integrity and curbing excessive tissue remodeling. It participates in critical processes including embryonic development, wound healing, and tissue repair. Furthermore, TIMP3 may play a role in pathologies marked by unregulated MMP activity, such as arthritis and cancer.
Shipping and Storage
This product is shipped with dry ice. It is recommended to aliquote as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months. Avoid repeated freezing and thawing.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL.Aliquote the reconstituted solution to minimise freeze-thaw cycles.