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Recombinant Bovine Deoxyribonuclease-1 (DNASE1)

Cat. No.AP7F499

Product TypeAnimal Proteins

Size 2000 U

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Product Overview

BioVenic's Recombinant Bovine Deoxyribonuclease-1 (DNASE1) is a recombinant protein expressed from Yeast. Its predicted molecular weight is 31.3 kDa.

Specifications

Type Recombinant Protein
Species Bovine
Expression System Yeast
Biological Activity ≥2 U/mL
Predicted Molecular Weight 31.3 kDa
Physical State Liquid
Formulation 5 mM Calcium Acetate, 4 mg/ml glycine (stabilizer), pH 5.0 and 50% glycerol.

Target Information

Deoxyribonuclease 1 (DNase I), also known as DNase 1, is an endonuclease enzyme that plays a crucial role in cleaving the phosphodiester bonds within the DNA backbone. It acts as the molecular scissors, specifically targeting double-stranded DNA and breaking it down into smaller fragments. Deoxyribonuclease 1 is encoded by the DNASE1 gene in cattle. It is a nuclease of relatively low specificity which interacts with DNA in the minor groove.

Protein Bovine Deoxyribonuclease-1 (DNASE1)
Protein Synonym Deoxyribonuclease-1; DNASE1; Deoxyribonuclease I; DNase I; DNL1
Gene ID 282217
UniProt ID P00639
EC No. 3.1.21.1

Shipping and Storage

This product is shipped with dry ice. Avoid repeated freezing and thawing. Store at -20°C.

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquote the reconstituted solution to minimise freeze-thaw cycles.

References

  1. Cal, S. et al. Conversion of bovine pancreatic DNase I to a repair endonuclease with a high selectivity for abasic sites. The EMBO journal. 1998, 17: 7128-7138.
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