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Recombinant African Swine Fever Virus Ubiquitin-conjugating Enzyme E2 (ASFV UBC), N-His
Product Overview
BioVenic's Recombinant African Swine Fever Virus Ubiquitin-conjugating Enzyme E2 (ASFV UBC), N-His is a recombinant protein expressed from E.coli Expression System. Its predicted molecular weight is 25.0 kDa. The purity is>90% (SDS-PAGE).
Specifications
Target Information
The ASFV I215L gene encodes the only known viral ubiquitin-conjugating (E2) enzyme, a critical regulator of the host's protein degradation machinery. It facilitates the transfer of ubiquitin to specific substrates, playing a pivotal role in viral gene transcription and genome replication. Beyond its catalytic function, I215L acts as an immune modulator by targeting host proteins like IRF3 and NF-kappa B for degradation, effectively suppressing the innate immune response. Its unique status as a viral E2 enzyme makes it a high-priority target for antiviral drug screening.
Shipping and Storage
This product is shipped with gel ice bags. Avoid repeated freezing and thawing. Store for 12 months at -20°C or -80°C.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquote the reconstituted solution to minimise freeze-thaw cycles.