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Recombinant Lake Victoria Marburgvirus Envelope Glycoprotein 1 (GP1), C-Fc
Product Overview
BioVenic's Recombinant Lake Victoria Marburgvirus Envelope Glycoprotein 1 (GP1), C-Fc is a recombinant protein expressed from Mammalian Expression System. Its predicted molecular weight is 71.2 kDa. The purity is>90% (SDS-PAGE).
Specifications
Target Information
GP1 is the surface-exposed subunit of the Marburgvirus spike glycoprotein, responsible for host cell attachment. It contains the critical Receptor-Binding Domain (RBD) that targets Niemann-Pick C1 (NPC1) within host endosomes. GP1 is heavily glycosylated with N-linked and O-linked glycans, forming a "glycan shield" that protects the virus from immune neutralization. Its primary role is to tether the virion to the cell surface and guide the virus into the endocytic pathway for subsequent membrane fusion.
Shipping and Storage
This product is shipped with gel ice bags. Avoid repeated freezing and thawing. Store for 12 months at -20°C or -80°C.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquote the reconstituted solution to minimise freeze-thaw cycles.