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Rabbit Anti-Rat Proteinase 3 (PR3) Polyclonal Antibody

Cat. No.VD2N555

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for rat proteinase 3. It is purified by Protein A Purified . It can be applied to WB, IHC, ICC and IP assays of rat proteinase 3.

Specifications

Application WB; IHC; ICC; IP
Clonality Polyclonal
Classification Primary Antibody
Clone Y1N54
Host Rabbit
Target Species Rat
Species Reactivity Rat
Specificity Rat Proteinase 3
Isotype IgG
Immunogen Recombinant protein of rat proteinase 3
Purification Protein A Purified
Concentration 0.5 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer Phosphate Buffered Saline, pH 7.4, with 50% glycerol
Physical State Liquid

Target Information

Rat proteinase 3 (PR3) is a serine protease primarily found in the azurophilic granules of neutrophils and lysosomes of monocytes. It plays a crucial role in the immune response by degrading bacterial proteins and modulating inflammation. PR3 is also involved in the processing of cytokines and chemokines. In autoimmune conditions, PR3 can become a target of autoantibodies, leading to diseases such as granulomatosis with polyangiitis.

Target Rat Proteinase 3
Target Synonym MBN; PRTN3; ACPA; AGP7; C-ANCA; MBT; P29; PRK; Myeloblastin; Serine Proteinase,Neutrophil,Wegener Granulomatosis Autoantigen
Gene ID 314615
UniProt ID F7FNG0

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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