This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Rabbit Anti-Canine Endothelial NOS (eNOS) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for canine endothelial NOS. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of canine endothelial NOS.
Specifications
Target Information
Canine endothelial nitric-oxide synthase (eNOS, NOS3) is a 133 kDa homodimeric flavo-heme enzyme whose oxygenase domain converts L-arginine to nitric oxide while its reductase domain shuttles electrons from NADPH through FAD and FMN. A solvent-exposed 16-aa "KVE" loop (aa 495-510) between the heme and BH4 pockets folds into a β-hairpin unique among canine NOS isoforms, presenting a conformational epitope preserved after phosphorylation and fixation. Affinity-purified antibodies targeting this loop trace native eNOS in pulmonary artery endothelium, cardiac capillaries, and renal glomeruli, delivering crisp cytoplasmic puncta and single-band clarity on immunoblots with no cross-reaction to nNOS or iNOS.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.