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Rabbit Anti-Rat Nephroblastoma Overexpressed Gene (NOV) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for rat nephroblastoma overexpressed gene. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of rat nephroblastoma overexpressed gene.
Specifications
Target Information
Rat nephroblastoma overexpressed gene (NOV/CCN3) is a secreted matricellular protein encoded by the Nov gene in Rattus norvegicus, mapped to chromosome 8. It belongs to the CCN protein family, featuring a conserved modular structure including IGF-binding domain, VWC module, TSP1 domain and a C-terminal CT domain. It localizes primarily to extracellular matrix and interstitial fluid, with tissue-specific expression in rat kidney, vascular tissues, brain and bone, with minimal levels in visceral organs. The protein mediates cell-matrix interaction and cell adhesion regulation, with conserved motifs critical for structural stability and ligand binding. Rat NOV shares core functional domains with mammalian orthologs, and has distinct tissue distribution differentiating it from other CCN family members.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.