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Rabbit Anti-Mouse Protein Tyrosine Kinase 2 Beta (PYK2) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse protein tyrosine kinase 2 beta. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of mouse protein tyrosine kinase 2 beta.
Specifications
Target Information
Mouse protein tyrosine kinase 2 beta (PTK2B) is a non-receptor tyrosine kinase of the focal adhesion kinase family, a core mediator of cell adhesion and stress-responsive signaling. It features a conserved N-terminal FERM domain for membrane and protein binding, a central catalytic kinase domain critical for substrate phosphorylation, and a C-terminal focal adhesion targeting motif. It localizes predominantly to the cytoplasm and focal adhesion sites of mouse fibroblasts, neuronal cells and immune cells, with negligible expression in terminally differentiated erythrocytes. The protein mediates signal transduction cascades via tyrosine phosphorylation, with conserved structural motifs differentiating it from PTK2 and other non-receptor kinases.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.