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Rabbit Anti-Rat Myogenin (MYOG) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for rat myogenin. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of rat myogenin.
Specifications
Target Information
Rat myogenin is a 224-residue basic helix-loop-helix transcription factor that binds the consensus E-box motif CANNTG within muscle-specific promoters. The bHLH domain (residues 85-140) mediates DNA contact and obligatory heterodimerization with E12/E47, while an adjacent C-terminal activation region rich in alanine and serine drives transcriptional output. Expressed exclusively in differentiating myoblasts and mature skeletal muscle fibers, the protein localizes to euchromatic nuclei and myonuclei. Antibodies raised against full-length or bHLH-specific peptides detect native, phosphorylated and truncated isoforms with negligible cross-reactivity to MyoD or Myf5, enabling precise immunoblot and immunohistochemical detection in rat skeletal-muscle homogenates and cultured myotubes.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.