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Rabbit Anti-Rat Microfibrillar Associated Protein 2 (MFAP2) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for rat microfibrillar associated protein 2. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of rat microfibrillar associated protein 2.
Specifications
Target Information
Rat microfibrillar-associated protein 2 (MFAP2) is a 183-residue secreted glycoprotein composed of an N-terminal signal peptide, a central array of six tandem calcium-binding EGF-like repeats, and a C-terminal RGD motif that engages αVβ3 integrin. The polypeptide forms antiparallel disulfide-linked dimers via cysteines flanking the EGF array, yielding a 42 kDa species under non-reducing conditions. Constitutively expressed in aortic media, lung alveoli and dermal connective tissue, MFAP2 localizes to elastin-associated microfibrils and interelastic connections. Antibodies raised against full-length recombinant rat MFAP2 detect native, glycosylated and dimeric forms with negligible cross-reactivity to MFAP1, MFAP3 or fibrillin-1, enabling selective immunoblot and immunohistochemical visualization in rat tissue homogenates and sections.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.