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Rabbit Anti-Mouse Noggin (NOG) Polyclonal Antibody

Cat. No.VD2N673

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for mouse noggin. It is purified by Protein A Purified . It can be applied to WB, IHC, ICC and IP assays of mouse noggin.

Specifications

Application WB; IHC; ICC; IP
Clonality Polyclonal
Classification Primary Antibody
Clone Y1N172
Host Rabbit
Target Species Mouse
Species Reactivity Mouse
Specificity Mouse Noggin
Isotype IgG
Immunogen Recombinant protein of mouse noggin
Purification Protein A Purified
Concentration 1 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.05% Proclin 300
Buffer 0.01M Phosphate Buffered Saline, pH 7.4, with 50% glycerol
Physical State Liquid

Target Information

Mouse Noggin is a secreted protein that plays a crucial role in embryonic development and tissue homeostasis. It functions as an inhibitor of Bone Morphogenetic Proteins (BMPs) by binding to BMP ligands and preventing their interaction with receptors, thereby modulating BMP signaling pathways. Noggin is essential for neural induction, limb development, and the regulation of bone and cartilage formation. In adult tissues, it helps maintain tissue integrity and regulates inflammation. Dysregulation of Noggin is associated with developmental disorders and diseases. It is an important target for studying developmental biology and tissue engineering in mouse models.

Target Mouse Noggin
Target Synonym SYM1; SYNS1; Synostoses(Multiple)Syndrome 1; Symphalangism 1(Proximal)
Gene ID 18121
UniProt ID P97466

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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