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Rabbit Anti-Mouse Leptin Receptor (LEPR) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse leptin receptor. It is affinity purified by protein A. It can be applied to WB and IHC assays of mouse leptin receptor.
Specifications
Target Information
Mouse Leptin Receptor is a key protein involved in regulating energy balance and metabolism. It is a member of the class I cytokine receptor family and is expressed in various tissues, including the hypothalamus, liver, and adipose tissue. This receptor binds to leptin, a hormone produced by adipocytes, and mediates its signaling effects. Activation of the leptin receptor triggers multiple intracellular signaling pathways, including the JAK/STAT pathway, which plays a crucial role in regulating appetite, body weight, and glucose metabolism. In mice, the leptin receptor is essential for maintaining energy homeostasis and metabolic balance.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 2 years). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- McMurphy, Travis, et al. "The anti-tumor activity of a neutralizing nanobody targeting leptin receptor in a mouse model of melanoma." PloS one 9.2 (2014): e89895.