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Rabbit Anti-Mouse Immunoglobulin E (IgE) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse immunoglobulin E. It is affinity purified by protein A. It can be applied to WB, IHC, ICC and IP assays of mouse immunoglobulin E.
Specifications
Target Information
Mouse IgE is a class of antibodies that play a central role in allergic reactions and immune responses against parasites. It is produced by plasma cells and has a unique structure with two heavy chains and two light chains. IgE binds to high-affinity FcεRI receptors on mast cells and basophils, triggering the release of histamine and other inflammatory mediators upon allergen exposure. This antibody is also involved in the immune defense against helminth infections. IgE levels can be elevated in conditions such as allergies and parasitic infections.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 2 years). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Oshiba, Akihiro, et al. "Passive transfer of immediate hypersensitivity and airway hyperresponsiveness by allergen-specific immunoglobulin (Ig) E and IgG1 in mice." The Journal of clinical investigation 97.6 (1996): 1398-1408.