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Rabbit Anti-Mouse Lamin B1 (LMNB1) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse lamin B1. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of mouse lamin B1.
Specifications
Target Information
Mouse lamin B1 is a 66 kDa type-V intermediate filament whose central α-helical rod and C-terminal immunoglobulin fold assemble head-to-tail tetramers, forming a stable meshwork beneath the inner nuclear membrane. A solvent-exposed 14-aa "KVE" loop (aa 415-428) between coil 2B and the tail linker folds into a β-hairpin unique among mouse lamins, presenting a conformational epitope preserved after nuclear envelope isolation and fixation. Affinity-purified antibodies targeting this loop trace native lamin B1 in nuclear lamina, replication factories, and mitotic spindle envelopes, delivering crisp perinuclear rings and single-band clarity on immunoblots with no cross-reaction to lamin A/C or lamin B2.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.