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Rabbit Anti-Mouse Huntingtin (HTT) Polyclonal Antibody

Cat. No.VD2N837

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for mouse huntingtin. It is purified by Protein A Purified . It can be applied to WB, IHC, ICC and IP assays of mouse huntingtin.

Specifications

Application WB; IHC; ICC; IP
Clonality Polyclonal
Classification Primary Antibody
Clone Y1N336
Host Rabbit
Target Species Mouse
Species Reactivity Mouse
Specificity Mouse Huntingtin
Isotype IgG
Immunogen Recombinant protein of mouse huntingtin
Purification Protein A Purified
Concentration 0.5 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.05% Proclin 300
Buffer 0.01M Phosphate Buffered Saline, pH 7.4, with 50% glycerol
Physical State Liquid

Target Information

Mouse Huntingtin is a large protein involved in various cellular processes, including vesicle trafficking, gene transcription, and neuronal function. It is expressed in neurons and other cell types, where it plays a crucial role in maintaining cellular homeostasis. Mutations in the huntingtin gene can lead to the production of an abnormally long polyglutamine tract, causing the protein to misfold and aggregate, which is associated with Huntington's disease. Understanding the normal function of huntingtin is essential for elucidating the pathogenesis of this neurodegenerative disorder.

Target Mouse Huntingtin
Target Synonym IT15; HD; Interesting Transcript 15; Huntington disease protein
Gene ID 15194
UniProt ID P42859

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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