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Rabbit Anti-Mouse Hemoglobin Alpha 1 (HBa1) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse hemoglobin alpha 1. It is purified by protein A/G. It can be applied to WB and IHC assays of mouse hemoglobin alpha 1.
Specifications
Target Information
Mouse hemoglobin alpha 1 (HBA1) is a globin polypeptide subunit that heterotetramerizes with HBB subunits to form functional hemoglobin (Hb) in erythrocytes, a core mediator of oxygen and carbon dioxide transport. It features a conserved globin fold with a heme-binding pocket, hydrophobic amino acid motifs for subunit interaction, and structural domains critical for allosteric oxygen binding. It localizes exclusively to the cytoplasm of mouse red blood cells, with negligible expression in non-hematopoietic tissues. The protein mediates gas exchange between tissues and lungs, with conserved residues for heme iron coordination. Mouse HBA1 shares core functional domains with mammalian orthologs, and has distinct oxygen affinity differentiating it from HBA2 and embryonic globins.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
