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Rabbit Anti-Mouse BMX Non Receptor Tyrosine Kinase (BMX) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse BMX non receptor tyrosine kinase. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of mouse BMX non receptor tyrosine kinase.
Specifications
Target Information
Mouse BMX non receptor tyrosine kinase is an intracellular kinase encoded by the Bmx gene in Mus musculus, mapped to chromosome 3. It belongs to the Tec family of non-receptor tyrosine kinases, featuring a conserved N-terminal pleckstrin homology domain, Tec homology region, Src-homology 3 and 2 domains, and a C-terminal catalytic kinase domain. It localizes to cytoplasm and cell membrane, with tissue-specific expression in mouse myeloid cells, endothelial cells and platelets, with minimal levels in epithelial tissues. The protein mediates intracellular signal transduction, with conserved motifs for activation and substrate phosphorylation. Mouse BMX shares core functional domains with mammalian orthologs, and has distinct tissue distribution differentiating it from Tec, Btk and other family members.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.