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Rabbit Anti-Bovine Matrix Gla Protein (MGP) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for bovine matrix Gla protein. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of bovine matrix Gla protein.
Specifications
Target Information
Bovine matrix Gla protein (MGP) is a 14 kDa secreted γ-carboxyglutamate-rich protein whose five Gla residues and C-terminal serine-phosphorylated tail bind calcium crystals and collagen I, anchoring to vascular and cartilage extracellular matrices. A solvent-exposed 16-aa "KVE" loop (aa 35-50) between the second and third Gla domains folds into a β-hairpin unique among bovine Gla proteins, presenting a conformational epitope preserved after carboxylation and fixation. Affinity-purified antibodies targeting this loop trace native MGP in aortic media, growth-plate cartilage, and tendon insertions, delivering crisp extracellular tracks and single-band clarity on immunoblots with no cross-reaction to osteocalcin or prothrombin.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.