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Mouse Obestatin (OB) ELISA Kit-Competitive

Cat. No.EK5F898

Product TypeAnimal Immunoassay Kits

Size 96T

Product Overview

BioVenic Mouse Obestatin (OB) ELISA Kit-Competitive is designed for the quantitative determination of Mouse OB in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Competitive ELISA method. For research use only.

Specifications

Assay Type ELISA-Competitive
Specificity The assay kit is specific for Mouse Obestatin (OB).
Target Species Mouse
Species Reactivity Mouse
Detection Range 78.25-5000 pg/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

Obestatin is a 23-amino acid peptide hormone produced from the ghrelin gene, and in mice, it plays a role in several physiological processes such as energy balance, metabolic regulation, and the functioning of the gastrointestinal and endocrine systems. One of its significant functions is appetite suppression, as it is known to reduce food consumption by activating the GPR39 receptor and can lead to reduced weight gain when administered chronically over the long term. Obestatin significantly impacts gastrointestinal function, such as slowing the gastric emptying rate without affecting gastric contractions. Additionally, it influences gastrointestinal motility by altering the mechanical activity and electrophysiological properties of gastric smooth muscle. In metabolic regulation, obestatin is critical as it enhances insulin secretion, particularly in response to glucose, and helps prevent apoptosis and the inflammatory response in adipocytes through the activation of the AMPK signaling pathway.

Target/Biomarker Mouse OB
Target Synonym Obestatin

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Pradhan, Geetali et al. "Obestatin stimulates glucose-induced insulin secretion through ghrelin receptor GHS-R." Scientific reports vol. 7,1 979. 20 Apr. 2017.
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