Mouse Glucagon Like Peptide 1 (GLP1) ELISA Kit-Competitive

Glucagon-like peptide 1 (GLP-1) is an incretin hormone produced by intestinal L cells, primarily functioning through the activation of the GLP-1 receptor (GLP-1R). In mice, GLP-1 serves various physiological roles, such as regulating blood sugar, safeguarding neurons, exerting anti-inflammatory effects, and enhancing cardiovascular and renal function. It stabilizes blood sugar by increasing insulin secretion from pancreatic β cells and inhibiting glucagon release. Research indicates that GLP-1 can significantly lower blood sugar levels in mice and enhance insulin sensitivity, which is especially critical in diabetic models. Moreover, GLP-1 slows gastric emptying and decreases food intake, aiding in the control of body weight and blood sugar levels. It is also expressed in the central nervous system, where it protects neurons from oxidative stress and apoptosis by activating GLP-1R.