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Recombinant Bovine Monocyte Differentiation Antigen CD14 (CD14), C-His

Cat. No.AP2C260

Product TypeAnimal Proteins

Size

Product Overview

BioVenic's Recombinant Bovine Monocyte Differentiation Antigen CD14 (CD14), C-His is a recombinant protein expressed from HEK293 Cell. Its predicted molecular weight is 40.5 kDa. The purity is>95% (SDS-PAGE).

Specifications

Type Recombinant Protein
Species Bovine
Expression System HEK293 Cell
Purity >95% (SDS-PAGE)
Endotoxin < 1.0 EU/mg
Predicted Molecular Weight 40.5 kDa
Physical State Lyophilized
Formulation PBS with 5% Trehalose and 5% Mannitol.

Target Information

Bovine Monocyte Differentiation Antigen CD14 (CD14) is a crucial immune molecule expressed on monocytes and macrophages. CD14 plays a key role in innate immunity by recognizing and binding pathogen-associated molecular patterns (PAMPs), such as lipopolysaccharide (LPS), thereby activating inflammatory responses. Additionally, CD14 is expressed in bovine mammary epithelial cells, where it modulates their response to LPS, enhancing pathogen recognition. In the bovine immune system, CD14 also regulates the differentiation and function of monocytes, promoting their conversion into tissue macrophages and dendritic cell precursors.

Protein Bovine Monocyte Differentiation Antigen CD14 (CD14)
Protein Synonym CD14 antigen; CD14 molecule; CD14
Gene ID 281048
UniProt ID Q95122

Shipping and Storage

This product is shipped with ice packs. Lyophilized protein can be stored at -20°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquot the reconstituted solution to minimize freeze-thaw cycles.
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