This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Rabbit Anti-Rat Toll Like Receptor 5 (TLR5) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for rat toll like receptor 5. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of rat toll like receptor 5.
Specifications
Target Information
Rat toll like receptor 5 (TLR5) is a transmembrane pattern recognition receptor of the TLR family, a core mediator of innate immune responses to bacterial components. It features an N-terminal leucine-rich repeat (LRR) domain for flagellin binding, a single transmembrane segment, and a C-terminal Toll/interleukin-1 receptor (TIR) domain critical for downstream signal transduction. It localizes predominantly to the plasma membrane of rat intestinal epithelial cells and immune cells like macrophages, with negligible expression in non-mucosal and non-immune tissues. The protein mediates TIR-domain dependent signaling assembly, with conserved structural motifs differentiating it from TLR4 and TLR9.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.