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Rabbit Anti-Rat Bactericidal/Permeability Increasing Protein (BPI) Polyclonal Antibody

Cat. No.VD2N981

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for rat bactericidal/permeability increasing protein. It is purified by Protein A Purified . It can be applied to WB, IHC, ICC and IP assays of rat bactericidal/permeability increasing protein.

Specifications

Application WB; IHC; ICC; IP
Clonality Polyclonal
Classification Primary Antibody
Clone Y1N480
Host Rabbit
Target Species Rat
Species Reactivity Rat
Specificity Rat Bactericidal/Permeability Increasing Protein
Isotype IgG
Immunogen Recombinant protein of rat bactericidal/permeability increasing protein
Purification Protein A Purified
Concentration 0.5 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer Phosphate Buffered Saline, pH 7.4, with 50% glycerol
Physical State Liquid

Target Information

Rat Bactericidal/Permeability-Increasing Protein (BPI) is a key component of the immune system, primarily found in neutrophils. It plays a crucial role in host defense against bacterial infections by binding to bacterial lipopolysaccharides, leading to bacterial membrane permeabilization and cell death. BPI also modulates inflammatory responses and enhances the clearance of pathogens. As a potent antimicrobial protein, BPI is an important target for studying innate immunity and potential therapeutic applications in infectious diseases.

Target Rat Bactericidal/Permeability Increasing Protein
Target Synonym CAP 57
Gene ID 296321
UniProt ID Q6AXU0

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Jin, Hongkui, et al. "Protection against endotoxic shock by bactericidal/permeability-increasing protein in rats." The Journal of clinical investigation 95.4 (1995): 1947-1952.
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