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Rabbit Anti-Mouse Thioredoxin (TRX) Polyclonal Antibody

Cat. No.VD1N26

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for mouse thioredoxin. It is affinity purified by protein A. It can be applied to WB, IHC, ICC and IP assays of mouse thioredoxin.

Specifications

Application WB; IHC; ICC; IP
Clonality Polyclonal
Classification Primary Antibody
Clone A1N26
Host Rabbit
Target Species Mouse
Species Reactivity Mouse
Specificity Mouse Thioredoxin
Isotype IgG
Immunogen Recombinant protein of mouse thioredoxin
Purification Protein A Purified
Concentration 0.5 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.05% Proclin 300
Buffer 0.01M Phosphate Buffered Saline, pH 7.4, with 50% Glycerol
Physical State Liquid

Target Information

Mouse Thioredoxin (TRX) is a key oxidoreductase enzyme that plays a crucial role in maintaining cellular redox homeostasis. It contains a highly conserved active site with two vicinal cysteines (Cys32/35) that enable its oxidoreductase activity by reducing oxidized cysteines and disulfide bridges in target proteins. TRX is involved in various cellular functions, including antioxidant defense, apoptosis regulation, autophagy, cytoskeleton organization, and signaling transduction. It interacts with multiple proteins, such as ASK-1, mTOR, and peroxiredoxins, and helps regulate thiol switches in response to oxidative stress.

Target Mouse Thioredoxin
Target Synonym TXN; ADF; SASP; TRDX; TRX1; ATL-derived factor; Surface-associated sulphydryl protein
UniProt ID P10639

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 2 years). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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