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Rabbit Anti-Mouse Tar DNA Binding Protein 43kDa (TDP43) Polyclonal Antibody

Cat. No.VD3N133

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for mouse TAR DNA binding protein 43kDa. It is purified by Protein A Purified . It can be applied to WB, IHC, ICC and IP assays of mouse TAR DNA binding protein 43kDa.

Specifications

Application WB; IHC; ICC; IP
Clonality Polyclonal
Classification Primary Antibody
Clone Y1N631
Host Rabbit
Target Species Mouse
Species Reactivity Mouse
Specificity Mouse Tar DNA Binding Protein 43kDa
Isotype IgG
Immunogen Recombinant protein of mouse TAR DNA binding protein 43kDa
Purification Protein A Purified
Concentration 0.5 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.05% Proclin 300
Buffer 0.01M Phosphate Buffered Saline, pH 7.4, with 50% glycerol
Physical State Liquid

Target Information

Mouse TAR DNA Binding Protein 43kDa (TDP-43) is a nuclear protein involved in RNA processing and transcriptional regulation. It binds to TAR DNA sequences and plays a role in stabilizing RNA molecules. TDP-43 is also implicated in neurodegenerative diseases due to its tendency to aggregate in affected neurons. Targeting TDP-43 with specific antibodies allows for detailed investigation of its localization, function, and pathological role in neurodegenerative conditions, making it a valuable tool for understanding disease mechanisms and potential therapeutic interventions.

Target Mouse Tar DNA Binding Protein 43kDa
Target Synonym TARDBP; ALS10
Gene ID 230908
UniProt ID Q921F2

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Nishimoto, Yoshinori, et al. "Characterization of alternative isoforms and inclusion body of the TAR DNA-binding protein-43." Journal of Biological Chemistry 285.1 (2010): 608-619.
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