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Rabbit Anti-Mouse Lipase A Lysosomal Acid (LIPA) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse lipase A lysosomal acid. It is affinity purified by protein A. It can be applied to WB, IHC, ICC and IP assays of mouse lipase A lysosomal acid.
Specifications
Target Information
Mouse Lipase A, also known as lysosomal acid lipase or cholesterol ester hydrolase, is a key enzyme responsible for the hydrolysis of cholesteryl esters and triglycerides in lysosomes. This enzyme is essential for lipid metabolism and is encoded by the Lipa gene. Defects in this gene can lead to severe lipid storage disorders, such as Wolman disease and cholesteryl ester storage disease. Lysosomal acid lipase is synthesized as a precursor polypeptide and undergoes glycosylation and lysosomal targeting. It plays a crucial role in maintaining cholesterol homeostasis and is involved in various cellular processes, including macrophage activation and lipid mediator synthesis.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 2 years). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.