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Mouse Dendritic Cell Line-DC2.4

Product Overview

DC2.4 cells are immortalized murine dendritic cells generated by transducing C57BL/6 mouse bone marrow isolates with a retroviral vector expressing murine granulocyte-macrophage CSF (GM-CSF) and the myc and raf oncogenes. DC2.4 cells exhibit characteristic dendritic cell features, including typical cellular morphology, expression of dendritic cell-specific markers, and the ability to phagocytose and present exogenous antigens on both MHC class I and class II molecules. These cells are a widely used experimental model for investigating dendritic cell (DC) function and immune responses.

Specifications

Cell Product Type Cell Line

Species Mouse

Cell Type Dendritic Cells

Source Bone Marrow

Growth Information Suspension and loosely adherent; 37°C; 5%CO₂

Quality Control Mycoplasma (-); Bacteria (-); Yeast (-); Fungi (-)

Formulation and Cell Culture Medium RPMI-1640 with 10% FBS; 1% Penicillin-Streptomycin Solution

Physical State Frozen cells

Shipping and Storage

This product is shipped with dry ice. It's recommended to store the product with liquid nitrogen and never in a -20 °C or -80 °C refrigerator. Avoid repeated freezing and thawing of the product.

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.