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Rabbit Anti-Sheep Transforming Growth Factor Beta 1 (TGFb1) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for sheep transforming growth factor beta 1. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of sheep transforming growth factor beta 1.
Specifications
Target Information
Sheep transforming growth factor beta 1 (TGF-β1) is a 112-residue mature cytokine released from a 390-amino-acid pro-protein through furin cleavage. The biologically active entity is a 25 kDa disulfide-linked homodimer stabilized by nine intra-chain and one inter-chain cystine, adopting an extended "cystine-knot" fold that presents two symmetrical receptor-binding surfaces. Stored in platelet α-granules and secreted by activated leukocytes, fibroblasts and endothelial cells, the dimer circulates bound to latency-associated peptide and latent TGF-β binding proteins. Antibodies raised against recombinant ovine TGF-β1 detect both the latent complex and mature dimer with negligible cross-reactivity to TGF-β2 or TGF-β3, enabling direct measurement in sheep plasma, tissue extracts and culture supernatants.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.