Mouse Circadian Locomoter Output Cycles Protein Kaput (CLOCK) ELISA Kit-Sandwich

Circadian locomotor output cycles protein kaput (CLOCK) is a transcriptional activator and a pivotal component of the circadian clock. This internal time-keeping mechanism regulates various physiological processes by producing approximately 24-hour rhythms in gene expression, influencing metabolism and behavior. In mice, CLOCK is also integral to several biological processes, including neuronal development, neurotransmitter regulation, and maintaining neuronal function. For instance, the knockout of the CLOCK gene results in cognitive dysfunction, mood disorders, and a diminished response to drugs, highlighting its essential role in the nervous system. Additionally, CLOCK influences gene expression and circadian rhythm stability by regulating histone acetylation levels.