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Mouse Embryonic Osteoblasts Cell-MC3T3-E1 Subclone 14
Product Overview
Mouse Embryonic Osteoblasts Cell-MC3T3-E1 is an osteoblast precursor cell line derived from the calvaria of newborn mice, possessing high osteogenic differentiation potential. It's characterized by high alkaline phosphatase (ALP) activity at confluence, which is a significant marker of osteoblast differentiation. This cell line has over ten subclones and serves as an excellent in vitro model for studying osteoblast differentiation, particularly extracellular matrix (ECM) signaling pathways. It's an ideal material for research into bone cell biology, bone metabolism, and osteosarcoma, among other areas. MC3T3 subclone 4 and MC3T3 subclone 14 showed high levels of osteoblastic differentiation when grown in ascorbic acid and 3 to 4 mM inorganic phosphate.
Specifications
Shipping and Storage
This product is shipped with dry ice. It's recommended to store the product with liquid nitrogen and never in a -20 °C or -80 °C refrigerator. Avoid repeated freezing and thawing of the product.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.