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Mouse Embryonic Osteoblasts Cell-MC3T3-E1 Subclone 14

Product Overview

Mouse Embryonic Osteoblasts Cell-MC3T3-E1 is an osteoblast precursor cell line derived from the calvaria of newborn mice, possessing high osteogenic differentiation potential. It's characterized by high alkaline phosphatase (ALP) activity at confluence, which is a significant marker of osteoblast differentiation. This cell line has over ten subclones and serves as an excellent in vitro model for studying osteoblast differentiation, particularly extracellular matrix (ECM) signaling pathways. It's an ideal material for research into bone cell biology, bone metabolism, and osteosarcoma, among other areas. MC3T3 subclone 4 and MC3T3 subclone 14 showed high levels of osteoblastic differentiation when grown in ascorbic acid and 3 to 4 mM inorganic phosphate.

Specifications

Cell Product Type Cell Line

Species Mouse

Cell Type Osteoblasts

Source Embryo Mouse Skull

Growth Information Adherent; 37°C; 5%CO₂

Quality Control Mycoplasma (-); Bacteria (-); Yeast (-); Fungi (-)

Formulation and Cell Culture Medium MEMα with 10% FBS; 1% Penicillin-Streptomycin Solution

Physical State Frozen cells

Shipping and Storage

This product is shipped with dry ice. It's recommended to store the product with liquid nitrogen and never in a -20 °C or -80 °C refrigerator. Avoid repeated freezing and thawing of the product.

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.