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Zebrafish(Danio rerio)
Zebrafish (Danio rerio) are small, freshwater tropical fish native to the streams, ponds, and rice paddies of India's northeast. They have slender bodies decorated with striking blue and silver stripes on both sides of their bodies, hence their name. They have become a pivotal model organism in scientific research due to several key characteristics that make them highly suitable for various fields of study.
Zebrafish, as versatile model organisms, play a crucial role in diverse scientific disciplines such as developmental biology, genetics, neuroscience, disease research, toxicology, and drug discovery. It has high embryo yield, fast reproduction speed, transparent embryos and low maintenance cost. It has many physiological structures similar to humans, and its genetic background is clear. The genome has 70% homology with humans. Due to their physiological relevance to humans, they are crucial in toxicology and drug discovery. Overall, zebrafish has advanced the study of biological mechanisms and therapeutic strategies, providing crucial insights into human health.
Fig. 1 Application of Zebrafish Model in Human
Disease Research. (Adhish M, Manjubala I, 2023)
Drug Discovery
Neuroscience
Disease Research
Toxicology Studies
BioVenic provides a range of basic experimental services dedicated to supporting the success of your research projects. Our services include but are not limited to:
Harnessing cutting-edge gene editing technology, we perform gene transfer as well as knock-in and knock-out (KI/KO) studies in aquatic models to elucidate the intricate roles of specific genes in disease onset and progression.
Aquatic Animal Models Development
Tailor-made zebrafish models are crafted to align seamlessly with your research objectives, spanning domains such as cancer, cardiovascular ailments, and neurodegenerative disorders.
Aquatic Animal Phenotype Analysis
Detailed phenotype analysis reveals behavioral, physiological, and molecular changes in zebrafish under different conditions, enhancing understanding of disease mechanisms.
We provide extensive molecular data spanning genomics, transcriptomics, proteomics, metabolomics, single-cell sequencing, and epigenetics analysis.
Zebrafish was used as a model for general toxicity tests, such as acute toxicity assay and embryonic teratogenicity assay, to evaluate the safety of the compounds.
Organ-specific Toxicity Assays
Accurately evaluate the response of target organs such as liver, heart and nervous system, and more accurately understand the potential toxicity risk.
Pharmacokinetic Analysis
We provide services for pharmacokinetic analysis using zebrafish, efficiently evaluating the absorption, distribution, metabolism, and excretion characteristics of drugs in the body.
Biological Efficacy Evaluation
We use zebrafish to evaluate the biological efficacy of cosmetics and health foods, in order to scientifically verify their actual effects on health and beauty.
Professional Team
Customized Services
Innovative Technology
Efficient Services
Whether you are an academic research institution, biotechnology company, or pharmaceutical industry, we can provide the highest quality support and services for your research projects. Looking forward to working with you to promote the progress of scientific research together! If you need further information about our services, please feel free to contact us.
Reference
Our products and services are for research use only and cannot be used for any clinical purposes.