Embryo Acute Test

Embryo acute test, specifically designed for aquatic animals, assesses the immediate toxic effects of substances on the early-stage development of aquatic embryos. This test provides critical insights into the potential risks posed by chemicals, pharmaceuticals, and environmental pollutants to aquatic life. BioVenic offers specialized services for conducting embryo acute tests on aquatic species, supporting environmental safety evaluations and regulatory compliance in aquatic ecosystems.

Introduction to Embryo Acute Test

The Embryo Acute Test uses fish embryos, like zebrafish, to assess the acute effects of chemicals, offering a more ethical alternative to traditional testing with adult fish. Widely recognized for its reliability in chemical risk assessments and regulatory evaluations, FET aligns with the 3Rs principles, helping to reduce animal testing while still providing critical toxicity data. The test is increasingly used in water quality monitoring and environmental impact assessments. Recent advances in automation are improving its efficiency, making it a key method in environmental toxicology and supporting high throughput testing in regulatory settings.

Fig. 1 Workflow of embryo acute test.

Applications of Embryo Acute Test

The FET is a valuable tool in assessing the potential risks posed by various substances. Its applications span across several fields to provide essential insights into the safety and environmental impact of chemicals.

• Chemical Risk Assessment: FET is used to evaluate the acute toxicity of chemicals, including industrial chemicals, pesticides, and biocides, providing critical data for hazard classification and safety evaluations.
• Water Quality Monitoring: It helps assess the toxicity of waterborne pollutants, such as heavy metals, pharmaceuticals, and other contaminants, ensuring the safety of aquatic environments.
• Environmental Impact Assessment: FET is used to evaluate the potential ecological risks of new chemicals or substances before they are released into the environment.
• Ecotoxicology Research: FET serves as a model for studying the effects of environmental contaminants on aquatic organisms during early development, helping to identify mechanisms of toxicity.

Our Services

BioVenic has extensive experience in conducting embryo acute toxicity tests on aquatic animals. We offer comprehensive FET services using various fish species, including zebrafish, to assess the acute toxic effects of chemicals.

Workflow of Our Service

Egg Collection

Zebrafish eggs are collected and inspected to ensure quality. Only healthy, viable eggs are selected for testing.

Experiment Setup

The selected eggs are exposed to varying concentrations of the test substance. The exposure setup is arranged in petri dishes or multiwell plates, ensuring controlled conditions for accurate assessment.

Development Monitoring

The embryos are monitored for development, recording any significant morphological changes or toxic effects. Key observations include the progression from egg to embryo and early signs of coagulation in affected samples.

Mortality & Morphology Assessment

Embryos are closely observed for signs of mortality, malformations, or coagulation. Dead embryos and abnormal developments are recorded for toxicity evaluation.

Data Analysis & Reporting

Data collected throughout the test period is analyzed to determine the acute toxicity of the substance. A detailed technical report is generated, providing insights into dose-response relationships and potential environmental risks.

Why Choose Us?

With a team of experienced toxicologists and aquaculture experts, BioVenic offers comprehensive and cost-effective testing solutions for environmental research. Specialized in assessing chemical toxicity in aquatic species, the company provides reliable services that prioritize ethical and scientifically advanced methods. The embryo acute toxicity test for aquatic animals ensures accurate, timely results, supporting your research efforts with high-quality data. For more information or to discuss your specific needs, please contact us.

Our products and services are for research use only and cannot be used for any clinical purposes.

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