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Aquatic Animal Immunotoxicity Assay Service
Immunotoxicity refers to the harmful effects of exogenous substances on the immune system. These effects may manifest themselves in the form of immunosuppression, immunostimulation, hypersensitivity, or autoimmune reactions, which can lead to abnormalities in the functioning of the immune system and an increased risk of infection, inflammation, or immune-related diseases. At BioVenic, we offer high-quality data, innovative solutions, and precise analyses for immunotoxicity assay to support aquatic animal research.
Immunotoxicity assay evaluates the effects of compounds, drugs, pollutants, or other substances on the immune system, focusing on immune cell survival, proliferation, differentiation, cytokine secretion, phagocytosis, and cytotoxicity to determine immunosuppressive or immunostimulatory effects. The multi-parameter evaluation of the immunotoxicity assay can be enhanced by combining it with techniques like flow cytometry, ELISA, and qPCR. Additionally, the assay's high sensitivity enables the detection of potential effects from low-dose compounds on the immune system, making it suitable for high-throughput drug screening and increasing research efficiency.
Fig. 1 Examine the immunotoxic effects of insecticides on fish. (Yang, et al., 2021)
Immunotoxicity assay with aquatic animals is widely used in drug discovery and development, toxicological assessment, and immune disease research. It can be used to study diseases of the immune system in aquatic organisms, to monitor water pollution by assessing changes in immune cell activity or cytokine levels, or in marine ecology to study the effects of environmental factors on the immune function of aquatic animals.
Environment and Ecology
Species and Genetics
Disease Research Model
Drug Development
The immunotoxicity assay is a comprehensive assessment of the immune response and toxic effects of aquatic organisms to environmental pollutants, drugs, feed additives, heavy metals, microplastics, and other substances. BioVenic is committed to advancing the frontiers of aquatic biology research. We do this by using state-of-the-art detection technologies and by applying scientific rigor and innovative technological solutions.
Immune Function Assessment
We provide a variety of professional services to evaluate how different pollutants and compounds affect the immune system. Our offerings include flow cytometry, immunohistochemistry, immune cell counting and phenotyping tools, phagocytosis monitoring, and techniques for analyzing immune-related gene expression.
Immunotoxicity Screening
In addition to offering services for the screening of chemical substances for toxicity using ELISA technology, we also offer drug immunotoxicity screening services such as immune spectroscopy based on the easily culturable and economical aquatic animals as experimental models, including atlantic salmon.
Immunohistopathological Analysis
Pathological analyses of the immune-related organs in mexican cavefish, cichlid, and others, such as the spleen and liver, are conducted to assess the impact of toxic substances on tissue structure and function.
Immunotoxicity-related Gene Expression Analysis
In aquatic animals exposed to toxic substances, immune-related genes are analyzed and mechanisms are revealed for the effects toxic substances have on the immune system.
Professional Team
Customized Services
Innovative Technology
Efficient Services
BioVenic values scientific rigor and innovation. We combine the most stringent scientific practices with the latest technology to offer cutting-edge research methodologies from universities that support your research efforts. Contact us, and together we can accelerate the advancement of aquatic biology research, creating a healthier and more sustainable aquatic ecosystem.
Reference
Our products and services are for research use only and cannot be used for any clinical purposes.