- Email:
- Phone:
- Add:
Aquatic Animal Developmental Toxicity Assay Service
Developmental toxicity assay is an experimental method used to assess the potential harm of chemicals, drugs, or other exogenous substances to embryos and developing organisms. At BioVenic, we are committed to providing our clients with high-quality data and in-depth analyses to help identify and solve a variety of problems in research and development drugs and aquatic environments, including pollution, ecological imbalances, and species conservation.
Developmental toxicity assay studies the growth, morphological changes, and physiological and behavioral responses of aquatic animal embryos or larvae during development by exposing them to specific chemicals or contaminants. It is essential in toxicology, evaluating the harmful effects of chemicals, drugs, or environmental agents on organism development during embryonic and early postnatal stages. Advanced testing models, including fish embryos (e.g., Danio rerio), amphibians (Xenopus laevis), crustacean (Daphnia magna), mollusks, and other aquatic species, are often utilized to conduct comprehensive toxicity assessments.
Fig. 1 Explore the developmental toxicity of anti-epileptics in zebrafish embryos and larvae. (Hoyberghs, J., et al., 2024)
Developmental toxicity assay with aquatic organisms is primarily used to screen for potentially toxic compounds and to ensure that new drugs, chemicals, or other products do not harm aquatic organisms' development and ecosystems before they reach the market. Furthermore, it facilitates the identification of sources of pollution in the aquatic environment and the assessment of their toxic effects on aquatic organisms. The development toxicity test is also used to investigate the effects of agricultural pesticides on water bodies and their biological communities, in particular on embryonic development and early growth, as well as pollution's long-term effects on aquatic communities' structure and function.
Aquatic Ecology
Species and Genetics
Physiology and Behavior
Drug Development
At BioVenic, our cutting-edge assays assess the impact of environmental pollutants, chemicals, and new substances on the development of aquatic species, from embryos to juvenile stages. With a focus on accuracy and reliability, we will provide you with a pre-assessment of cardiotoxicity to minimize potential risks in drug development. Trust us to deliver high-quality, science-driven solutions that protect aquatic life and promote a healthier, more sustainable environment.
Behavior and Locomotor Activity Analysis
The objective of the service is to examine the impact of the substance under investigation on the post-developmental behavior and locomotor abilities of aquatic animals. This includes assessing range of motion and swimming speed.
Malformation and Mutation Studies
During the development of aquatic animal embryos and larvae, the compound is tested to determine whether it causes malformations or genetic mutations. This is achieved by monitoring the process of embryonic development.
Ecotoxicity Assessment
Our services include the evaluation of the ecotoxicological effects of substances on aquatic animals. We utilize several aquatic animals as experimental models to assess the toxic effects of various pollutants, such as rainbow trout.
Biomarker Analysis
We will use it to evaluate toxic effects on aquatic animals by studying how the substance affects biomarkers in embryos and larvae, like BMPs, AChE, or P53.
The following is a list of the types of aquatic organisms we offer, but they are not limited to:
Professional Team
Customized Services
Innovative Technology
Efficient Services
BioVenic is the expert choice for aquatic developmental toxicity testing. We are committed to providing a personal and tailored service using advanced technology, accurate data analysis and rigorous quality control. Below is a list of related services we can provide, please contact us if you require further information.
Reference
Our products and services are for research use only and cannot be used for any clinical purposes.
