- Email:
- Phone:
- Add:
Aquatic Animal Muscle Toxicity Assay Service
The muscle toxicity assay is an experimental method for assessing the toxicity of drugs or other compounds to muscle cells (e.g., skeletal or cardiac muscle cells). BioVenic is committed to providing personalized research solutions and technical support to meet the diverse needs of research teams while promoting sustainable research methods and harmony between humans and nature.
Due to exogenous chemical substances on the muscle tissue caused by direct or indirect damage, such as muscle fiber damage, dysfunction, and other impact on the ability to exercise, physiological function damage, such a toxic effect is known as muscle toxicity. The muscle toxicity assay is designed to evaluate the effects of chemicals, pollutants, drugs, and other substances on the muscle tissue of aquatic organisms. This assay quantitatively measures the toxic response of muscle tissues in aquatic organisms when exposed to different external chemicals, utilizing a range of molecular, histological, and physiological methods.
Fig. 1 explore the role of Cox7a1 in muscle physiology and heart regeneration. (Carolina García-Poyatos, et al., 2024)
Muscle toxicity assay in aquatic organisms not only provides important support for solving related diseases and assist in the screening and development of related drugs but also provides a basis for ecosystem restoration studies in terms of the biochemical changes that occur in muscle tissues when they are affected by compounds.
Aquatic Ecology
Genetics
Disease Research
Physiology and Behavior
The muscle toxicity assay has various applications in aquatic biology research, encompassing areas such as ecotoxicology, aquaculture, drug screening, food safety, metabolic studies, and the investigation of molecular mechanisms. BioVenic is dedicated to delivering tailored services that ensure comprehensive and insightful toxicity analysis.
Acute Toxicity Test
An acute toxicity study can be conducted on aquatic animals such as medaka, which has a rapid life circle and a short developmental cycle exposed to various concentrations of the test substance for a short period. Deaths, symptoms of poisoning, and so on were observed and recorded during this study.
Co-toxicity Test
If the combined effects of multiple pollutants or drug on the muscles of aquatic animals need to be studied, combined toxicity experiments can be conducted to analyze the combined toxic effects, such as synergistic, antagonistic, or additive effects.
Chronic Toxicity Test
Chronic toxic effects on the growth, development, physiology, and function of aquatic organisms' muscles, such as muscle growth retardation and muscle atrophy, can be observed by exposing the subjects to low doses over a long period.
Immunotoxicity Test
Whether the immune function of muscles is suppressed or activated is assessed by detecting the effects of the test substance on the muscle immune indicators of aquatic organisms, such as changes in the number and activity of immune cells and changes in the expression of relevant genes.
Professional Team
Customized Services
Innovative Technology
Efficient Services
At BioVenic, we are committed to advancing the frontiers of aquatic biology research. We do this by applying a rigorous scientific approach and innovative technical solutions. Whether you are exploring the mysteries of aquatic ecosystems or optimizing the environmental monitoring and protection of aquatic organisms, we can provide you with customized and professional solutions. Please feel free to contact us when you have a need.
Reference
Our products and services are for research use only and cannot be used for any clinical purposes.