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African Green Monkey Kidney Cells-COS-1

Product Overview

African Green Monkey Kidney Cells-COS-1 are an immortalized cell line widely used in scientific research. This cell line was derived from the CV-1 cell line through transfection with SV40 containing an origin-defective mutation encoding the wild-type T-antigen. COS-1 cells have a constitutively expressed copy of the entire early region of the SV40 genome integrated, thus enabling them to support the replication of SV40 virus and its variants (such as the temperature-sensitive A209 virus) at high temperatures.

Specifications

Cell Product Type Cell Line

Species Monkey

Cell Type Fibroblasts

Source Kidney

Growth Information Adherent; 37°C; 5%CO₂

Quality Control Mycoplasma (-); Bacteria (-); Yeast (-); Fungi (-)

Formulation and Cell Culture Medium DMEM (containing NAHCO3 1.5 g/L) with 10% FBS; 1% Penicillin-Streptomycin Solution

Physical State Frozen cells

Target Information

These cells are transformed and stably express the large T-antigen of the simian virus 40 (SV40T antigens) to immortalize the cells and extend their lifespan.

Target/Biomarker SV40T antigens

Target Synonym large T antigen [ Simian virus 40 ]

Gene ID 1489531

Shipping and Storage

This product is shipped with dry ice. It's recommended to store the product with liquid nitrogen and never in a -20 °C or -80 °C refrigerator. Avoid repeated freezing and thawing of the product.

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.