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Mouse Cardiomyocyte Cell Line-HL-1

Cat. No.CC7F58

Product TypeAnimal Cells and Cell Lines

Product Overview

Mouse Cardiomyocyte Cell Line-HL-1 was established in 1997 from a subcutaneous tumor excised from an adult female C57BL/6J inbred mouse. This mouse was transgenic, having been transfected with a fusion gene consisting of the atrial natriuretic factor promoter and the SV40 region. HL-1 cells are an immortalized mouse cardiomyocyte cell line capable of continuous division and spontaneous contraction while maintaining a differentiated cardiac phenotype. HL-1 cells can be serially passaged without losing their differentiated, specific cardiomyocyte phenotype, including morphological, biochemical, and electrophysiological characteristics. They are commonly used to study the functions of normal cardiomyocytes in signal transduction, cell metabolism, and transcriptional regulation, as well as to simulate pathological conditions in vitro such as hypoxia, hyperglycemia-hyperinsulinemia, apoptosis, and ischemia-reperfusion.

Specifications

Cell Product Type Cell Line
Species Mouse
Cell Type Cardiomyocytes
Source Heart
Growth Information Adherent; 37°C; 5%CO2
Quality Control Mycoplasma (-); Bacteria (-); Yeast (-); Fungi (-)
Formulation and Cell Culture Medium Claycomb Medium with 10% FBS; 0.1mM Norepinephrine; 2 mM L-Glutamine; 1% Penicillin-Streptomycin Solution
Physical State Frozen cells

Shipping and Storage

This product is shipped with dry ice. It's recommended to store the product with liquid nitrogen and never in a -20 °C or -80 °C refrigerator. Avoid repeated freezing and thawing of the product.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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