Autogenous veterinary vaccines are biologics prepared using pathogens and antigens isolated from infected animals. These customized vaccines allow for targeting only relevant pathogens in specific animal populations, avoiding unnecessary vaccinations for unrelated diseases. Autogenous veterinary vaccines are an excellent choice for large farms with the aim of customization for animal populations, low immunotoxicity, and minimized costs. Drawing from our extensive experience, BioVenic has established a platform to help you develop customized autogenous vaccines to combat pathogens in livestock, poultry, and aquaculture species, addressing pathogen threats and safeguarding animal health.
Types of Pathogens
Autogenous veterinary vaccines derive their active components from bacterial or viral strains associated with animal diseases. The table below lists some of the types of animal pathogens that can be targeted using autogenous veterinary vaccines.
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Types
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Common Pathogens
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Bacteria
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Streptococcus, Salmonella, Mycoplasma, Haemophilus, Staphylococcus, Clostridium, Moraxella, Escherichia coli, Corynebacterium, Pasteurella, Riemerella, Erysipelothrix.
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Virus
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Paramyxovirus, Infectious Bronchitis Virus, low-path Avian Influenza Virus, Adenovirus, Infectious Bursal Disease virus, Avian Reovirus.
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Our Services
BioVenic provides one-stop services for autogenous veterinary vaccine development services covering a wide range of animal types, including swine, cattle, poultry, and aquatic. Here is the brief workflow.
The correct isolation, and identification of strains are the first crucial steps in autogenous veterinary vaccine development, which are of paramount importance for the quality, safety, and expected efficacy. BioVenic possesses expertise in these areas and has established laboratories with the necessary infrastructure to advance projects.
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Sampling and Culture
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Professionals from BioVenic extract tissues from diseased animals, and inoculate the processed samples onto a suitable medium that fosters pathogen growth.
BioVenic provides an optimal environment for the growth of bacterial pathogens. In the case of viral pathogens, we supply host cells or chicken embryos to support the growth and development of viruses.
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Identification
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For bacterial identification, BioVenic offers basic results through observations of colony morphology, Gram staining, and biochemical tests.
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For viral pathogens, we offer serological tests and use techniques like immunoelectron microscopy to determine their morphology and species.
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We utilize molecular methods and mass spectrometry methods to provide more accurate viral and bacterial identification results.
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The formulation of vaccines, especially adjuvants, plays a crucial role in the efficacy of autogenous veterinary vaccines. Adjuvants not only enhance the intensity of the immune response but also determine the type of immune response generated (cell-mediated or humoral). BioVenic provides vaccine formulation development services, conducting experiments to match adjuvants with your specific antigens to achieve the best protective immune response. Additionally, we take responsibility for the selection and incorporation of components such as excipients and stabilizers in the formulation of autogenous veterinary vaccines.
BioVenic implements stringent quality control during autogenous veterinary vaccine development, providing safety and field performance assurance. Assays include sterility testing, inactivation verification, endotoxin residue testing and inactivator residue testing, ensuring that the following parameters meet the requirements for use.
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Purity of the pathogen targets throughout isolation, recombination, purification, and identification processes.
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CO2/O2 ratio, optimal growth curves, nutrient additives, pH, and temperature in the pathogen growth environment.
Our Advantages
Extensive experience in developing autogenous veterinary vaccines for various pathogens and animal types.
Providing emergency vaccines for newly emerging animal diseases in the absence of commercial vaccines.
Offering solutions for infections involving variant antigens of the same species or serotype.
Stringent quality control processes to ensure the highest levels of safety for veterinary vaccines.
Autogenous veterinary vaccines provide immunization programs in commercial vaccine absence or immunization failure, which also can be simplified by combining several valencies. BioVenic has established the platform for autogenous veterinary vaccine development, assisting you in developing personalized vaccines tailored to specific needs, laying a strong foundation for immunizing animal populations. If you're interested, please contact us now to discuss your ideas!
