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Recombinant Zebrafish Leptin (LEP)

Product Overview

BioVenic's Recombinant Zebrafish Leptin (LEP) is a recombinant protein expressed from E.coli. Its predicted molecular weight is 16.5 kDa. The purity is>95% (SDS-PAGE).

Specifications

Type Recombinant Protein

Species Zebrafish

Expression System E.coli

Purity >95% (SDS-PAGE)

Predicted Molecular Weight 16.5 kDa

Physical State Lyophilized

Formulation NaHCO3.

Target Information

Leptin, encoded by the LEP gene in zebrafish, is believed to be involved in a signaling pathway that regulates body fat depot size. This hormone, secreted by adipocytes, travels through the bloodstream, crosses the blood-brain barrier (BBB), and binds to its receptor, LepR. This interaction is known to negatively regulate appetite.

Protein Zebrafish Leptin (LEP)

Protein Synonym leptin; OB

Gene ID 548631

UniProt ID Q588G0

Shipping and Storage

This product is shipped with dry ice. Avoid repeated freezing and thawing. Store at -20°C.

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquote the reconstituted solution to minimise freeze-thaw cycles.

References

Audira, Gilbert et al. "Zebrafish Mutants Carrying Leptin a (lepa) Gene Deficiency Display Obesity, Anxiety, Less Aggression and Fear, and Circadian Rhythm and Color Preference Dysregulation." International journal of molecular sciences vol. 19,12 4038. 13 Dec. 2018