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Recombinant Tickborne Encephalitis Virus NS5 Protein (TBEV NS5), N-His

Cat. No.VG3F285

Product TypeVeterinary Antigens

Size

Product Overview

BioVenic's Recombinant Tickborne Encephalitis Virus NS5 Protein (TBEV NS5), N-His is a recombinant protein expressed from E.coli Expression System. Its predicted molecular weight is 32.0 kDa. The purity is>90% (SDS-PAGE).

Specifications

Type Recombinant Protein
Species Virus
Expression System E.coli Expression System
Purity >90% (SDS-PAGE)
Predicted Molecular Weight 32.0 kDa
Physical State Lyophilized
Formulation PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.

Target Information

TBEV NS5 is the largest and most conserved non-structural protein of the Tick-borne Encephalitis Virus, serving as the primary enzymatic engine for viral replication. It contains two functional domains: an N-terminal methyltransferase (MTase) responsible for RNA capping and a C-terminal RNA-dependent RNA polymerase (RdRp) for genome synthesis. Beyond replication, NS5 is a potent antagonist of the host innate immune response, specifically inhibiting interferon signaling. Its essential role makes it a premier target for broad-spectrum antiflaviviral drug development.

Protein Tickborne Encephalitis Virus NS5 Protein (TBEV NS5)
Protein Synonym TBEV Non-structural protein 5; RNA-dependent RNA polymerase (RdRp); TBEV methyltransferase; NS5-TBEV; Tick-borne encephalitis virus NS5

Shipping and Storage

This product is shipped with gel ice bags. Avoid repeated freezing and thawing. Store for 12 months at -20°C or -83°C.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquote the reconstituted solution to minimise freeze-thaw cycles.
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