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Recombinant Swine Uricase (UOX), N-His

Cat. No.AP3F35

Product TypeAnimal Proteins

Size

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Product Overview

BioVenic's Recombinant Swine Uricase (UOX), N-His is a recombinant protein expressed from E.coli Expression System. Its predicted molecular weight is 37.2 kDa. The purity is>90% (SDS-PAGE).

Specifications

Type Recombinant Protein
Species Swine
Expression System E.coli Expression System
Purity >90% (SDS-PAGE)
Predicted Molecular Weight 37.2 kDa
Physical State Lyophilized
Formulation PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.

Target Information

Porcine Uricase (Urate Oxidase) is a homotetrameric liver enzyme that catalyzes the oxidation of uric acid into 5-hydroxyisourate, which is subsequently converted to allantoin.2 While the UOX gene is a non-functional pseudogene in humans and great apes, it remains highly active in swine. Due to its robust uricolytic activity, recombinant porcine uricase is extensively used in biochemical research and as a template for developing PEGylated therapeutic enzymes to treat hyperuricemia and tumor lysis syndrome in humans.

Protein Swine Uricase (UOX)
Protein Synonym Uricase; UO; Urate Oxygen Oxidoreductase; Urate:Oxygen Oxidoreductase; UOXP
Gene ID 397510
UniProt ID P16164

Shipping and Storage

This product is shipped with gel ice bags. Avoid repeated freezing and thawing. Store for 12 months at -20°C or -80°C.

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquote the reconstituted solution to minimise freeze-thaw cycles.
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