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Recombinant Swine Metalloproteinase Inhibitor 2 (TIMP2), N-His
Product Overview
BioVenic's Recombinant Swine Metalloproteinase Inhibitor 2 (TIMP2), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is N/A. The purity is>97% (SDS-PAGE).
Specifications
Target Information
Swine tissue inhibitors of metalloproteinase 2 (TIMP-2) is a regulatory protein composed of 194 amino acids with a molecular weight of around 21 kDa. It has dual functionality: reducing MMP activity and facilitating pro-MMP-2 activation. TIMP-2 is crucial for maintaining the structural and functional integrity of tissues, particularly in the kidneys, by regulating the extracellular matrix components.
Shipping and Storage
This product is shipped with dry ice. It is recommended to aliquote as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL.Aliquote the reconstituted solution to minimise freeze-thaw cycles.
References
- Meléndez, J. et al. Cloning and expression of guinea pig TIMP-2. Expression in normal and hyperoxic lung injury. American journal of physiology. Lung cellular and molecular physiology. 2000, 278,4: L737-43.