This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Recombinant Streptococcus pyogenes Streptokinase, N-His-SUMO
Product Overview
BioVenic's Recombinant Streptococcus pyogenes Streptokinase, N-His-SUMO is a recombinant protein expressed from E.coli Expression System. Its predicted molecular weight is 53.5 kDa. The purity is>90% (SDS-PAGE).
Specifications
Target Information
Streptokinase is a potent extracellular protein secreted by Streptococcus pyogenes (Group A Streptococcus) that acts as a highly specific plasminogen activator. Unlike human tissue plasminogen activator (tPA), SK does not have intrinsic enzymatic activity; instead, it forms a stoichiometric complex with host plasminogen, inducing a conformational change that converts it into active plasmin. This rapid fibrinolysis dissolves blood clots and degrades extracellular matrix proteins, facilitating the systemic spread of the bacteria through host tissues and contributing to invasive diseases like necrotizing fasciitis.
Shipping and Storage
This product is shipped with gel ice bags. Avoid repeated freezing and thawing. Store for 12 months at -20°C or -80°C.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquote the reconstituted solution to minimise freeze-thaw cycles.