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Recombinant Streptococcus pyogenes IgA Receptor Protein (arp4), N-His
Product Overview
BioVenic's Recombinant Streptococcus pyogenes IgA Receptor Protein (arp4), N-His is a recombinant protein expressed from E.coli Expression System. Its predicted molecular weight is 38.8 kDa. The purity is>90% (SDS-PAGE).
Specifications
Target Information
Arp4 is a surface-anchored protein of Streptococcus pyogenes (Group A Streptococcus) that specifically binds the Fc region of human Immunoglobulin A (IgA). By sequestering host IgA, Arp4 inhibits the recruitment of phagocytes and interferes with the classical complement pathway, effectively shielding the bacteria from mucosal immunity. This interaction is a sophisticated immune evasion strategy that facilitates bacterial colonization and persistence in the upper respiratory tract and skin.
Shipping and Storage
This product is shipped with gel ice bags. Avoid repeated freezing and thawing. Store for 12 months at -20°C or -80°C.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquote the reconstituted solution to minimise freeze-thaw cycles.
