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Recombinant Streptococcus pyogenes IgA Receptor Protein (arp4), N-His

Cat. No.VG3F258

Product TypeVeterinary Antigens

Size

Product Overview

BioVenic's Recombinant Streptococcus pyogenes IgA Receptor Protein (arp4), N-His is a recombinant protein expressed from E.coli Expression System. Its predicted molecular weight is 38.8 kDa. The purity is>90% (SDS-PAGE).

Specifications

Type Recombinant Protein
Species Bacteria
Expression System E.coli Expression System
Purity >90% (SDS-PAGE)
Predicted Molecular Weight 38.8 kDa
Physical State Lyophilized
Formulation PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.

Target Information

Arp4 is a surface-anchored protein of Streptococcus pyogenes (Group A Streptococcus) that specifically binds the Fc region of human Immunoglobulin A (IgA). By sequestering host IgA, Arp4 inhibits the recruitment of phagocytes and interferes with the classical complement pathway, effectively shielding the bacteria from mucosal immunity. This interaction is a sophisticated immune evasion strategy that facilitates bacterial colonization and persistence in the upper respiratory tract and skin.

Protein Streptococcus pyogenes IgA Receptor Protein (arp4)
Protein Synonym IgA-binding protein; Protein Arp; Arp4 protein; Group A Streptococcal IgA receptor
UniProt ID P13050

Shipping and Storage

This product is shipped with gel ice bags. Avoid repeated freezing and thawing. Store for 12 months at -20°C or -80°C.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquote the reconstituted solution to minimise freeze-thaw cycles.
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