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Recombinant Staphylococcus aureus Staphylokinase (sak), N-His
Product Overview
BioVenic's Recombinant Staphylococcus aureus Staphylokinase (sak), N-His is a recombinant protein expressed from E.coli Expression System. Its predicted molecular weight is 17.8 kDa. The purity is>90% (SDS-PAGE).
Specifications
Target Information
Staphylokinase is a 136-amino acid extracellular protein produced primarily by lysogenic strains of Staphylococcus aureus. It functions as a potent fibrin-specific plasminogen activator, forming a 1:1 complex with plasminogen to catalyze the formation of active plasmin. This activity facilitates tissue invasion by dissolving fibrin clots and degrading the extracellular matrix. Additionally, Sak promotes immune evasion by neutralizing host $\alpha$-defensins, making it a key virulence factor in skin infections and a significant target for thrombolytic research.
Shipping and Storage
This product is shipped with gel ice bags. Avoid repeated freezing and thawing. Store for 12 months at -20°C or -80°C.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquote the reconstituted solution to minimise freeze-thaw cycles.