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Recombinant Rabbit Immunoglobulin Heavy Constant Gamma (IgG Fc Fragment)
Product Overview
BioVenic's Recombinant Rabbit Immunoglobulin Heavy Constant Gamma (IgG Fc Fragment) is a recombinant protein expressed from Mammalian Expression System. Its predicted molecular weight is 27.5 kDa. The purity is>90% (SDS-PAGE).
Specifications
Target Information
The Rabbit IgG Fc Fragment is the "fragment crystallizable" tail region of the rabbit immunoglobulin G molecule, typically obtained via papain digestion. It consists of the CH2 and CH3 constant domains and the hinge region. While lacking the antigen-binding Fab sites, the Fc region is essential for mediating effector functions by binding to Fc receptors (FcγRs) on immune cells and C1q for complement activation. In biotechnology, it serves as a critical negative control, a standard in ELISA/Western blotting, and a structural scaffold for Fc-fusion proteins.
Shipping and Storage
This product is shipped with gel ice bags. Avoid repeated freezing and thawing. Store for 12 months at -20°C or -80°C.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquote the reconstituted solution to minimise freeze-thaw cycles.