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Recombinant Rabbit Complement Component C9 (C9), N-His
Product Overview
BioVenic's Recombinant Rabbit Complement Component C9 (C9), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 46.9 kDa. The purity is> 80%.
Specifications
Target Information
Rabbit Complement Component C9 (C9) is a vital protein in the complement system, participating in the formation of the Membrane Attack Complex (MAC). This complex assembles on bacterial membranes to form pores, disrupting membrane organization and leading to cell lysis. In rabbits, C9 is expressed in various tissues, including the heart, liver, spleen, and kidneys. It plays a critical role in immune defense against pathogens, as demonstrated in neonatal rats where C9 deficiency leads to increased susceptibility to bacterial infections. Additionally, C9 is involved in non-lethal cell-regulating functions and contributes to the release of lipopolysaccharide (LPS) from bacterial membranes. Its expression and function are essential for maintaining immune homeostasis and preventing infections.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10 mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.